2020/09/16 by S. Berteina-Raboin, M. Akssira
#Amino-tomentosin #Dittrichia Viscosa #Michael addition #Tomentosin
paper · doi:10.48317/imist.prsm/morjchem-v7i3.14007
In the present study, novel amino lactone derivatives of tomentosin 2 were efficiently prepared through a diastereoselective conjugate addition of several secondary amines to the α-methylene-γ-butyrolactone function of tomentosin 1, a sesquiterpene lactone extracted from Dittrichia viscosa. These compounds were fully characterized by spectroscopic methods.