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A Localization-to-Segmentation Framework for Automatic Tumor Segmentation in Whole-Body PET/CT Images

2023/09/11 by Linghan Cai, Cai, Linghan, Jianhao Huang +7 · 1 citation
Medicine · #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #FOS: Electrical engineering #Image and Video Processing (eess.IV) #Lung Cancer Diagnosis and Treatment #Medical Imaging Techniques and Applications #Radiomics and Machine Learning in Medical Imaging #electronic engineering #information engineering

paper · pdf · doi:10.48550/arxiv.2309.05446

openalex publication_date 2023/09/11 · openalex created_date 2023/09/13 · openalex updated_date 2026/07/28

Abstract

Fluorodeoxyglucose (FDG) positron emission tomography (PET) combined with computed tomography (CT) is considered the primary solution for detecting some cancers, such as lung cancer and melanoma. Automatic segmentation of tumors in PET/CT images can help reduce doctors' workload, thereby improving diagnostic quality. However, precise tumor segmentation is challenging due to the small size of many tumors and the similarity of high-uptake normal areas to the tumor regions. To address these issues, this paper proposes a localization-to-segmentation framework (L2SNet) for precise tumor segmentation. L2SNet first localizes the possible lesions in the lesion localization phase and then uses the location cues to shape the segmentation results in the lesion segmentation phase. To further improve the segmentation performance of L2SNet, we design an adaptive threshold scheme that takes the segmentation results of the two phases into consideration. The experiments with the MICCAI 2023 Automated Lesion Segmentation in Whole-Body FDG-PET/CT challenge dataset show that our method achieved a competitive result and was ranked in the top 7 methods on the preliminary test set. Our work is available at: https://github.com/MedCAI/L2SNet.

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