2021/05/18 by Yaowen Zhang, Jiaxing Gong, Zhang, Yaowen +12
Computer Science · Engineering · Physics and Astronomy · #Digital Imaging for Blood Diseases #FOS: Physical sciences #Medical Physics (physics.med-ph) #Optical Coherence Tomography Applications #physics.med-ph
paper · pdf · doi:10.48550/arxiv.2105.09306
arxiv created 2021/05/18 · openalex publication_date 2021/05/18 · arxiv updated 2021/05/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We investigated a new optical approach for the detection of the coagulation dynamic process by means of the information on the optical vortex. In our study, laser speckle was captured using a high-speed CMOS camera, and the statistical information of the optical vortex characterized the change in coagulation properties with time. Similar to the scattering particles, the motion of the optical vortex is restricted during coagulation, as a result, the whole process of coagulation can be detected by calculating the mean square displacement(MSD) of the optical vortex. The results demonstrate a close correlation between coagulation parameters measured using the optical vortex method and thrombelastography(TEG), creating a powerful opportunity for self-testing and real-time detection of coagulation.