2016/12/14 by Axel Krämer, Kramer, Axel, Ojan Assadian +3
Agricultural and Biological Sciences · Chemistry · Medicine · #610 Medical sciences #Antimicrobial agents and applications #Chlorhexidindigluconat #Dexpanthenol #Medicine #Phytochemistry Medicinal Plant Applications #Verstärkung der mikrobioziden Wirksamkeit #Wound Healing and Treatments #Wundantiseptik #chlorhexidine digluconate #dexpanthenol #enhancement of microbiocidal efficacy #wound antiseptic
paper · doi:10.3205/dgkh000284
openalex publication_date 2016/12/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/19
bactericidal and fungicidal efficacy required for a wound antiseptic under three different challenges, despite dilution to 55% of the original preparation. So far, the addition of dexpanthenol was intended to support wound healing. However, our results indicate that the antiseptic efficacy of CHX is synergistically increased by adding 5% dexpanthenol. Acknowledging the antimicrobial and residual efficacy of CHX, and bearing in the mind the contraindications to CHX (allergy and anaphylaxis), the tested wound cream should be regarded as better suitable to be used as wound antiseptic than preparations on basis of CHX alone.