Minor depression as a predictor of the first onset of major depressive disorder over a 15‐year follow‐up
2005/10/25 by J. Fogel, Joshua Fogel, W. W. Eaton +3 · 135 citations
Medicine · Psychology · #Anxiety #Child and Adolescent Psychosocial and Emotional Development #Clinical psychology #Depression (economics) #Injury prevention #Internal medicine #Logistic regression #Major depressive disorder #Major depressive episode #Medical emergency #Medicine #Mental Health Treatment and Access #Mood #Odds ratio #Poison control #Population #Psychiatry #Psychology #Risk factor #Suicidal ideation #Treatment of Major Depression
paper · doi:10.1111/j.1600-0447.2005.00654.x
published in Acta Psychiatrica Scandinavica 113(1), 36-43 (Wiley)
openalex publication_date 2005/10/25 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
Abstract
OBJECTIVE: To study the relationship of minor depression to first onset of major depressive disorder (MDD) among 1634 individuals over a 15-year follow-up using the Baltimore Epidemiologic Catchment Area cohort. METHOD: Logistic regression analyses were conducted with minor depression alone and also adjusting for anxiety, sociodemographic, and medical variables, with MDD as the outcome variable. Also, among those with minor depression, depressive symptom categories were studied with both logistic regression and population attributable risk (PAR) to determine if they predicted MDD. RESULTS: Individuals with a history of minor depression had an odds ratio of more than 5 of having a first lifetime episode of MDD (adjusted OR: 5.37, 95% CI: 2.87, 10.06). Suicidal ideation, appetite/weight issues, and sleep difficulty had the highest PARs. CONCLUSION: Minor depression strongly predicts MDD. Clinical and public health interventions for individuals with minor depression can potentially impact the pathway leading to MDD.
Cited by
- Depression and everyday social activity, belonging, and well-being.
- Greater incidence of depression with hypnotic use than with placebo. [europepmc]
- Associations of C-reactive protein and interleukin-6 with cognitive symptoms of depression: 12-year follow-up of the Whitehall II study. [europepmc]
- Environmental hazards and stress: evidence from the Texas City Stress and Health Study. [europepmc]
- Minor depression during adolescence and mental health outcomes during adulthood. [europepmc]
- Disparity in use of psychotherapy offered in primary care between older african-american and white adults: results from a practice-based depression intervention trial. [europepmc]
- The emerging modern face of mood disorders: a didactic editorial with a detailed presentation of data and definitions. [europepmc]
- Depression and Everyday Social Activity, Belonging, and Well-Being. [europepmc]
- Apathy and cognitive and functional decline in community-dwelling older adults: results from the Baltimore ECA longitudinal study. [europepmc]
- Cardiovascular and disease-related predictors of depression in systemic lupus erythematosus. [europepmc]
- The relationship of dysthymia, minor depression, and gender to changes in smoking for current and former smokers: longitudinal evaluation in the U.S. population. [europepmc]
- Concurrent trajectories of change in adolescent and maternal depressive symptoms in the TORDIA study. [europepmc]
- Neighborhood Hispanic composition and depressive symptoms among Mexican-descent residents of Texas City, Texas. [europepmc]
- Enhanced default mode network connectivity with ventral striatum in subthreshold depression individuals. [europepmc]
- Workplace sexual harassment and depressive symptoms: a cross-sectional multilevel analysis comparing harassment from clients or customers to harassment from other employees amongst 7603 Danish employees from 1041 organizations. [europepmc]
- Language Patterns Discriminate Mild Depression From Normal Sadness and Euthymic State. [europepmc]
- A Self-Paced, Web-Based, Positive Emotion Skills Intervention for Reducing Symptoms of Depression: Protocol for Development and Pilot Testing of MARIGOLD. [europepmc]
- Should antidepressants be used in minor depression? [europepmc]
- The Reliability and Validity of the Center for Epidemiologic Studies Depression Scale (CES-D) for Chinese University Students. [europepmc]
- The MARIGOLD study: Feasibility and enhancement of an online intervention to improve emotion regulation in people with elevated depressive symptoms. [europepmc]
- Effects Of Modified Mindfulness-Based Stress Reduction (MBSR) On The Psychological Health Of Adolescents With Subthreshold Depression: A Randomized Controlled Trial. [europepmc]
- Subthreshold Depression Needs A Prime Time In Old Age Psychiatry? A Narrative Review Of Current Evidence. [europepmc]
- A Deep Learning Approach for Mild Depression Recognition Based on Functional Connectivity Using Electroencephalography. [europepmc]
- Validation and Psychometric Properties of the Japanese Version of the Fear of COVID-19 Scale Among Adolescents. [europepmc]
- Impaired left amygdala resting state functional connectivity in subthreshold depression individuals. [europepmc]
- Altered spontaneous neural activity in the precuneus, middle and superior frontal gyri, and hippocampus in college students with subclinical depression. [europepmc]
Related