Evolution of the genetic code from the GC- to the AGUC-alphabet

2007/10/02 by Denis A. Semenov, Semenov, Denis A.
Biochemistry, Genetics and Molecular Biology · #Biomolecules (q-bio.BM) #FOS: Biological sciences #Populations and Evolution (q-bio.PE) #RNA and protein synthesis mechanisms

paper · pdf · doi:10.48550/arxiv.0710.0445

openalex publication_date 2007/10/02 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

A hypothesis of the evolution of the genetic code is proposed, the leading mechanism of which is the nucleotide spontaneous damage leading to AT-enrichment of the genome. The hypothesis accounts for stability of the genetic code towards point mutations, the presence of code dialects, and the symmetry of the genetic code table.

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