Spine distribution along the apical dendrites of the pyramidal neurons in Down's syndrome

1980/01/01 by Motohiro Suetsugu, M Suetsugu, Parviz Mehraein · 26 citations
Medicine · #Down syndrome and intellectual disability research

paper · doi:10.1007/bf00688755

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• Advanced microscopic imaging methods to investigate cortical development and the etiology of mental retardation. [europepmc]
• In vivo MRI identifies cholinergic circuitry deficits in a Down syndrome model. [europepmc]
• Normal protein composition of synapses in Ts65Dn mice: a mouse model of Down syndrome. [europepmc]
• Spatiotemporal Regulation of Signaling in and out of Dendritic Spines: CaMKII and Ras. [europepmc]
• Actin and Actin-Binding Proteins: Masters of Dendritic Spine Formation, Morphology, and Function. [europepmc]
• NMDA-mediated regulation of DSCAM dendritic local translation is lost in a mouse model of Down's syndrome. [europepmc]
• Casting a net on dendritic spines: the extracellular matrix and its receptors. [europepmc]
• Reversal of disease-related pathologies in the fragile X mouse model by selective activation of GABAB receptors with arbaclofen. [europepmc]
• Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. [europepmc]
• Dendritic spine dysgenesis in autism related disorders. [europepmc]
• Epigenetic regulation of neuronal dendrite and dendritic spine development. [europepmc]
• New Perspectives for the Rescue of Cognitive Disability in Down Syndrome. [europepmc]
• Where Environment Meets Cognition: A Focus on Two Developmental Intellectual Disability Disorders. [europepmc]
• A missense mutation in Katnal1 underlies behavioural, neurological and ciliary anomalies. [europepmc]
• A brain proteomic investigation of rapamycin effects in the Tsc1 +/- mouse model. [europepmc]
• Dendritic spine pathology and thrombospondin-1 deficits in Down syndrome. [europepmc]
• Intellectual disability: dendritic anomalies and emerging genetic perspectives. [europepmc]
• The actin binding protein drebrin helps to protect against the development of seizure-like events in the entorhinal cortex. [europepmc]
• Role of DSCAM in the Development of Neural Control of Movement and Locomotion. [europepmc]
• Dyrk1a from Gene Function in Development and Physiology to Dosage Correction across Life Span in Down Syndrome. [europepmc]
• Neurodevelopment in Down syndrome: Concordance in humans and models. [europepmc]
• Asynchronous excitatory neuron development in an isogenic cortical spheroid model of Down syndrome. [europepmc]
• From neurodevelopment to neurodegeneration: utilizing human stem cell models to gain insight into Down syndrome. [europepmc]
• Dysregulation of astrocyte-secreted pleiotrophin contributes to neuronal structural and functional deficits in Down syndrome. [europepmc]