2019/11/30 by Gerrit Hilgen, Hilgen, Gerrit
Neuroscience · #FOS: Biological sciences #Neural dynamics and brain function #Neurons and Cognition (q-bio.NC) #Neuroscience and Neural Engineering #Photoreceptor and optogenetics research
paper · pdf · doi:10.48550/arxiv.1912.00270
openalex publication_date 2019/11/30 · openalex created_date 2019/12/05 · openalex updated_date 2026/07/28
The advent of large-scale and high-density extracellular recording devices allows simultaneous recording from thousands of neurons. However, the complexity and size of the data makes it mandatory to develop robust algorithms for fully automated spike sorting. Here it is shown that limitations imposed by biological constraints such as changes in spike waveforms induced under different drug regimes should be carefully taken into consideration in future developments.