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Defying the Circadian Rhythm: Clustering Participant Telemetry in the UK Biobank Data

2020/11/17 by Nikola Počuča, Nikola Pocuca, Pocuca, Nikola +4
Environmental Science · Mathematics · Medicine · #Air Quality and Health Impacts #Applications (stat.AP) #FOS: Computer and information sciences #Health, Environment, Cognitive Aging #Physical Activity and Health #stat.AP

paper · pdf · doi:10.48550/arxiv.2011.08350

28 pages, 23 figures

arxiv created 2020/11/17 · openalex publication_date 2020/11/17 · arxiv updated 2020/11/18 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

The UK Biobank dataset follows over 500,000 volunteers and contains a diverse set of information related to societal outcomes. Among this vast collection, a large quantity of telemetry collected from wrist-worn accelerometers provides a snapshot of participant activity. Using this data, a population of shift workers, subjected to disrupted circadian rhythms, is analysed using a mixture model-based approach to yield protective effects from physical activity on survival outcomes. In this paper, we develop a scalable, standardized, and unique methodology that efficiently clusters a vast quantity of participant telemetry. By building upon the work of Doherty et al. (2017), we introduce a standardized, low-dimensional feature for clustering purposes. Participants are clustered using a matrix variate mixture model-based approach. Once clustered, survival analysis is performed to demonstrate distinct lifetime outcomes for individuals within each cluster. In summary, we process, cluster, and analyse a subset of UK Biobank participants to show the protective effects from physical activity on circadian disrupted individuals.

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