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Explainable Fundus Image Curation and Lesion Detection in Diabetic Retinopathy

2025/12/06 by Anca Mihai, Mihai, Anca, Adrian Groza +1
Medicine · #Artificial Intelligence (cs.AI) #Computer Vision and Pattern Recognition (cs.CV) #FOS: Computer and information sciences #Retinal Diseases and Treatments #Retinal Imaging and Analysis #Retinal and Optic Conditions

paper · pdf · doi:10.48550/arxiv.2512.08986

openalex publication_date 2025/12/06 · openalex created_date 2025/12/12 · openalex updated_date 2026/07/28

Abstract

Diabetic Retinopathy (DR) affects individuals with long-term diabetes. Without early diagnosis, DR can lead to vision loss. Fundus photography captures the structure of the retina along with abnormalities indicative of the stage of the disease. Artificial Intelligence (AI) can support clinicians in identifying these lesions, reducing manual workload, but models require high-quality annotated datasets. Due to the complexity of retinal structures, errors in image acquisition and lesion interpretation of manual annotators can occur. We proposed a quality-control framework, ensuring only high-standard data is used for evaluation and AI training. First, an explainable feature-based classifier is used to filter inadequate images. The features are extracted both using image processing and contrastive learning. Then, the images are enhanced and put subject to annotation, using deep-learning-based assistance. Lastly, the agreement between annotators calculated using derived formulas determines the usability of the annotations.

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