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Testing relevant difference in high-dimensional linear regression with applications to detect transferability

2025/11/19 by Liu, Xu
Engineering · Mathematics · #FOS: Computer and information sciences #Methodology (stat.ME) #Random Matrices and Applications #Sparse and Compressive Sensing Techniques #Statistical Methods and Inference

paper · doi:10.48550/arxiv.2511.15236

openalex publication_date 2025/11/19 · openalex created_date 2025/11/23 · openalex updated_date 2026/07/28

Abstract

Most of researchers on testing a significance of coefficient \ubeta in high-dimensional linear regression models consider the classical hypothesis testing problem H0c: \ubeta=\uzero versus H1c: \ubeta ≠ \uzero. We take a different perspective and study the testing problem with the null hypothesis of no relevant difference between \ubeta and \uzero, that is, H0: ‖\ubeta‖≤ δ0 versus H1: ‖\ubeta‖> δ0, where δ0 is a prespecified small constant. This testing problem is motivated by the urgent requirement to detect the transferability of source data in the transfer learning framework. We propose a novel test procedure incorporating the estimation of the largest eigenvalue of a high-dimensional covariance matrix with the assistance of the random matrix theory. In the more challenging setting in the presence of high-dimensional nuisance parameters, we establish the asymptotic normality for the proposed test statistics under both the null and alternative hypotheses. By applying the proposed test approaches to detect the transferability of source data, the unified transfer learning models simultaneously achieve lower estimation and prediction errors with comparison to existing methods. We study the finite-sample properties of the new test by means of simulation studies and illustrate its performance by analyzing the GTEx data.

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