Enantiopure hydroxymethylated cycloalkenols as privileged small molecular multifunctional scaffolds for the asymmetric synthesis of carbocycles

2023/09/13 by Kumar, R, Rej, RK, Halder, J +2

paper · doi:10.7302/8121

Abstract

Enantiopure hydroxymethylated cycloalkenols bearing a quaternary stereocenter have been synthesized by a Pybox mediated enantioselective desymmetrization method. The synthesized cycloalkenols serve as starting precursors for the construction of several chiral small ring carbocyclic frameworks by a distinct functional group transformation.

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