Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology

2025/01/01 by Lucien Hinderling, Remo Hadorn, Moritz Kwasny +9 · 2 voices · 1 citation
Engineering · #Microfluidic and Bio-sensing Technologies #Nanofabrication and Lithography Techniques #3D Printing in Biomedical Research

paper · pdf · doi:10.1039/d5lc00181a

Abstract

. Our protocol drastically reduces material costs compared to conventional methods and enables design-to-device turnaround within a day. By leveraging open-source microscope control software and existing lab equipment, our workflow lowers the entry barrier to microfabrication, enabling labs to prototype custom solutions for diverse experimental needs while maintaining compatibility with soft lithography and downstream biological assays.

Cited by

• Low-Cost Open Platform Digital Light Printer (OP-DLP) for 96-Well Format Hydrogel Printing and Localized Light-Activation. [europepmc]

Discussions

• PAPER OUT ✨ What if you could use your microscope as a 3D printer? Prototype microfluidics in-house, <5$ in material costs per chip. From idea to experiment within a day. Now published in Lab-on-a-Chi [bsky, 91 points, 4 comments]
• Teach your #microscope how to print: Low-cost rapid-iteration #OpenSource #microfabrication for #biology: -no cleanroom -replace SU-8 #photoresist & silicon wafers by #3Dprinting #resin & microscope [bsky, 6 points, 0 comments]

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