2023/08/30 by Surabhi Rathore, Rathore, Surabhi, Dasari Srikanth +1
Engineering · Medicine · #Blood properties and coagulation #FOS: Physical sciences #Fluid Dynamics (physics.flu-dyn) #Nanofluid Flow and Heat Transfer
paper · pdf · doi:10.48550/arxiv.2308.16047
openalex publication_date 2023/08/30 · openalex created_date 2023/09/02 · openalex updated_date 2026/07/28
The use of nanoparticles for targeted drug delivery, especially in diseased arteries, is a novel procedure. We are incorporating nanoparticles into blood vessels using a catheter, which could potentially deliver drugs precisely to affected areas, reducing side effects and increasing treatment efficiency. Considering non-Newtonian fluid modeling because blood is a complex fluid with non-linear behavior. In this paper, we are using mathematical modeling to understand blood flow dynamics, temperature, and concentration dispersion, which can provide valuable insights into the behavior of therapeutic nanoparticles in the bloodstream. The perturbation method is used to solve the complex mathematical model with permeable flow boundary conditions. We are investigating flow field characteristics including wall shear stress, pressure, and impedance to understand how nanoparticles disperse and interact with different physiological aspects. In conclusion, the proposed study focuses on the use of nanotechnology and mathematical modeling to understand the effects of therapeutic nanoparticles in diseased arteries, which is an important and valuable contribution to the medical field.