2024/07/13 by Cookey, Stella Ngozi, Gomba, Victoria Eno, Nwazor, Ernest O
#Alcohol #Cholesterol #Ethanol #HDL #LDL #Triglycerides
paper · doi:10.60787/tnhj.v22i2.578
Background: Though views of authors vary regarding moderate alcohol consumption, they however agree that excessive alcohol consumption has a deleterious effect on the cardiovascular system. Dyslipidaemia has been implicated as a risk factor for cardiovascular disease and mild to moderate alcohol consumption is said to be cardioprotective, though still a subject of debate. The study compared cholesterol parameters with daily alcohol consumption in residents of Rumuekini community. Methods: Forty-one male subjects had their blood samples collected after an overnight fast. Information on their occupation, symptoms and history of alcohol consumption were obtained using a questionnaire. The quantity of alcohol was assessed and the study population was divided into mild, moderate and severe based on amount of daily alcohol consumption. Results: Forty-one participants completed the study, age ranged from 19 to 91years with mean age of 34.49 ± 17.25yrs, mean systolic blood pressure of 128.10 ± 21.92mmHg, mean diastolic blood pressure of 77.20 ± 14.87mmHg and mean daily alcohol consumption was 74.24 ± 43.34g/day. The mean total cholesterol was 181.53 ± 41.43mg/dl, mean triglyceride was 139.84± 40.18mg/dl and mean low density lipoprotein was 79.34 ± 26.10 mg/dl while mean high density lipoprotein was 62.75 ± 13.54mg/dl. Excessive alcohol consumption was associated with lower total cholesterol, LDL and TG while moderate alcohol consumption was associated with higher HDL level. Conclusion: This study noted that alcohol generally reduced total cholesterol in a linear fashion, however this was at a summed effect of reducing LDL, increasing HDL and reducing TG.