2013/05/27 by Mark D. Robinson, Robinson, Mark D.
Biochemistry, Genetics and Molecular Biology · #Extracellular vesicles in disease #FOS: Biological sciences #MicroRNA in disease regulation #Molecular Biology Techniques and Applications #Other Quantitative Biology (q-bio.OT) #q-bio.OT
paper · pdf · doi:10.48550/arxiv.1305.6202
5 pages, 3 Supplemental PDFs
openalex publication_date 2013/05/27 · arxiv created 2013/06/10 · arxiv updated 2013/06/11 · openalex created_date 2022/10/01 · openalex updated_date 2026/07/28
This letter is a response to a Divergent Views article entitled <<The poor performance of TMM on microRNA-Seq>> (Garmire and Subramaniam 2013), which was a response to our Divergent Views article entitled <<miRNA-seq normalization comparisons need improvement>> (Zhou et al. 2013). Using reproducible code examples, we showed that they incorrectly used our normalization method and highlighted additional concerns with their study. Here, I wish to debunk several untrue or misleading statements made by the authors (hereafter referred to as GS) in their response. Unlike GSs, my claims are supported by R code, citations and email correspondences. I finish by making a call for better practice.