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Delving into LLM-assisted writing in biomedical publications through excess vocabulary

2024/06/11 by Dmitry Kobak, Rita González-Márquez, Kobak, Dmitry +5 · 24 voices · 114 citations
Computer Science · Medicine · Psychology · #Artificial Intelligence in Healthcare and Education #Coronavirus disease 2019 (COVID-19) #English language #Linguistics #Machine Learning in Healthcare #Mathematics education #Medicine #Pandemic #Pathology #Psychology #Topic Modeling #Vocabulary

paper · pdf · open access · doi:10.1126/sciadv.adt3813

published in Science Advances 11(27), eadt3813 (American Association for the Advancement of Science)

openalex publication_date 2025/07/02 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

Large language models (LLMs) like ChatGPT can generate and revise text with human-level performance. These models come with clear limitations, can produce inaccurate information, and reinforce existing biases. Yet, many scientists use them for their scholarly writing. But how widespread is such LLM usage in the academic literature? To answer this question for the field of biomedical research, we present an unbiased, large-scale approach: We study vocabulary changes in more than 15 million biomedical abstracts from 2010 to 2024 indexed by PubMed and show how the appearance of LLMs led to an abrupt increase in the frequency of certain style words. This excess word analysis suggests that at least 13.5% of 2024 abstracts were processed with LLMs. This lower bound differed across disciplines, countries, and journals, reaching 40% for some subcorpora. We show that LLMs have had an unprecedented impact on scientific writing in biomedical research, surpassing the effect of major world events such as the COVID pandemic.

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