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Mixed volumes of networks with binomial steady-states

2023/03/31 by Coons, Jane Ivy, Curiel, Mark, Gross, Elizabeth
#14M25 #52A39 #92E20 #Combinatorics (math.CO) #FOS: Mathematics

paper · doi:10.48550/arxiv.2303.18096

Abstract

The steady-state degree of a chemical reaction network is the number of complex steady-states for generic rate constants and initial conditions. One way to bound the steady-state degree is through the mixed volume of the steady-state system or an equivalent system. In this work, we show that for partionable binomial networks, whose resulting steady-state systems are given by a set of binomials and a set of linear (not necessarily binomial) conservation equations, computing the mixed volume is equivalent to finding the volume of a single mixed cell that is the translate of a parallelotope. We then turn our attention to identifying cycles with binomial steady-state ideals. To this end, we give a coloring condition on directed cycles that guarantees the network has a binomial steady-state ideal. We highlight both of these theorems using a class of networks referred to as species-overlapping networks and give a formula for the mixed volume of these networks.

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