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Unlocking the Power of Spatial and Temporal Information in Medical Multimodal Pre-training

2024/05/30 by Jinxia Yang, Bing Su, Yang, Jinxia +5 · 4 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · #Artificial Intelligence (cs.AI) #Biomedical Text Mining and Ontologies #FOS: Computer and information sciences #Intelligent Tutoring Systems and Adaptive Learning #Semantic Web and Ontologies

paper · pdf · doi:10.48550/arxiv.2405.19654

openalex publication_date 2024/05/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Medical vision-language pre-training methods mainly leverage the correspondence between paired medical images and radiological reports. Although multi-view spatial images and temporal sequences of image-report pairs are available in off-the-shelf multi-modal medical datasets, most existing methods have not thoroughly tapped into such extensive supervision signals. In this paper, we introduce the Med-ST framework for fine-grained spatial and temporal modeling to exploit information from multiple spatial views of chest radiographs and temporal historical records. For spatial modeling, Med-ST employs the Mixture of View Expert (MoVE) architecture to integrate different visual features from both frontal and lateral views. To achieve a more comprehensive alignment, Med-ST not only establishes the global alignment between whole images and texts but also introduces modality-weighted local alignment between text tokens and spatial regions of images. For temporal modeling, we propose a novel cross-modal bidirectional cycle consistency objective by forward mapping classification (FMC) and reverse mapping regression (RMR). By perceiving temporal information from simple to complex, Med-ST can learn temporal semantics. Experimental results across four distinct tasks demonstrate the effectiveness of Med-ST, especially in temporal classification tasks. Our code and model are available at https://github.com/SVT-Yang/MedST.

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