2020/10/30 by Michael Taynnan Barros, Barros, Michael Taynnan, Mladen Veletić +11 · 1 citation
Biochemistry, Genetics and Molecular Biology · Engineering · #Advanced biosensing and bioanalysis techniques #FOS: Biological sciences #FOS: Electrical engineering #Molecular Communication and Nanonetworks #Other Quantitative Biology (q-bio.OT) #Signal Processing (eess.SP) #Wireless Body Area Networks #electronic engineering #information engineering
paper · pdf · doi:10.48550/arxiv.2011.00002
openalex publication_date 2020/10/30 · openalex created_date 2022/07/25 · openalex updated_date 2026/07/28
Hundreds of millions of people worldwide are affected by viral infections\neach year, and yet, several of them neither have vaccines nor effective\ntreatment during and post-infection. This challenge has been highlighted by the\nCOVID-19 pandemic, showing how viruses can quickly spread and how they can\nimpact society as a whole. Novel techniques that bring in different disciplines\nmust emerge to provide forward-looking strategies to combat viral infections,\nas well as possible future pandemics. In the past decade, an interdisciplinary\narea involving bioengineering, nanotechnology and information and communication\ntechnology (ICT) has been developing, known as Molecular Communications. This\nnew emerging area uses elements of classical communication systems and maps it\nto molecular signalling and communication found inside and outside the body,\nwhere the aim is to develop new tools that can serve future medicine. In this\npaper, we provide an extensive and detailed discussion on how Molecular\nCommunications can be integrated into the research on viral infectious diseases\nmodelling, and how possible treatment and vaccines can be developed considering\nmolecules as information carriers. We provide a literature review on the\nexisting models of Molecular Communications for viral infection (in-body and\nout-body), a deep analysis on their effects on the host and subsequent\ncommunication process for other systems within the body (e.g., immune\nresponse), sources of experimental data on known viral infections and how it\ncan be used by the Molecular Communications community, as well as open issues\nand future directions. Since the development of therapeutics/vaccines needs an\ninterdisciplinary approach centred around ICT, we are confident that Molecular\nCommunications can play a central role here by providing a detail\ncharacterisation and manipulation of the propagation of molecules in different\nmedia.\n