2024/07/09 by Zohreh Sadeghi Rad, Sadeghi Rad, Zohreh, Farahmand, Mahnaz +2
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Acinetobacter baumannii #Antibiofilm #Antibiotic Resistance in Bacteria #Antimicrobial Peptides and Activities #Escherichia coli research studies #Medicine and health #Secapin #Zellverträglichkeit #antibiofilm #antimicrobial #antimikrobiell #bactericidal #bakterizid #cell compatibility
paper · doi:10.3205/dgkh000491
openalex publication_date 2024/07/09 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/19
Introduction: . Furthermore, the mechanisms underlying Secapin's antibacterial and antibiofilm activities were elucidated. Methods: biofilms was investigated. Hemolytic potential was evaluated using human red blood cells, while mammalian cell viability was examined at varying Secapin concentrations. Results: biofilms. Notably, Secapin exhibited no hemolytic activity and preserved mammalian cell viability up to a concentration of 100 µg/mL. Conclusion: , showcasing its efficacy in both antibacterial and antibiofilm capacities. The favorable attributes of Secapin, characterized by its minimal hemolytic effects and high mammalian cell viability, position it as a promising contender in the fight against antibiotic resistance.