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Data assimilation performed with robust shape registration and graph neural networks: application to aortic coarctation

2025/02/17 by Francesco Romor, Romor, Francesco, Felipe Galarce +7 · 1 citation
Decision Sciences · Engineering · #Energy Load and Power Forecasting #FOS: Mathematics #Numerical Analysis (math.NA) #Stock Market Forecasting Methods

paper · pdf · doi:10.48550/arxiv.2502.12097

openalex publication_date 2025/02/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Image-based, patient-specific modelling of hemodynamics can improve diagnostic capabilities and provide complementary insights to better understand the hemodynamic treatment outcomes. However, computational fluid dynamics simulations remain relatively costly in a clinical context. Moreover, projection-based reduced-order models and purely data-driven surrogate models struggle due to the high variability of anatomical shapes in a population. A possible solution is shape registration: a reference template geometry is designed from a cohort of available geometries, which can then be diffeomorphically mapped onto it. This provides a natural encoding that can be exploited by machine learning architectures and, at the same time, a reference computational domain in which efficient dimension-reduction strategies can be performed. We compare state-of-the-art graph neural network models with recent data assimilation strategies for the prediction of physical quantities and clinically relevant biomarkers in the context of aortic coarctation.

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