2024/12/30 by Hammami O ., Aloulou J ., Barbaria W . +1
#Acidocétose diabétique #Diabetes #Diabetic ketoacidosis #Diabète #Epidemiology #Resus- citation #Réanimation #Épidémiologie
paper · doi:10.71566/pist-rmp-194618
Diabetic ketoacidosis (DKA) is a life-threatening emergency requiring appropriate and urgent manage- ment. The aim of this study was to describe the epidemiological, clinical, therapeutic and evolutionary characteristics of children admitted to the pediatrics and neonatology department of Bizerte University Hospital for DKA. This was a retrospective study spanning five years from January 1, 2018 to December 31, 202, carried out in the pediatrics department of the Habib Bougatfa University Hospital in Bizerte, including all child- ren hospitalized for ACD and whose management was initiated in the department. We included 44 cases of ACD, 68% of which were inaugural. The mean age was 9±2 years, with a female predominance (gender-ratio=0. 4). Initial symptoms were dominated by a polyuro-polydipsic syndrome (n=10), asthenia (n=23), abdominal pain (n=14) and vomiting (n=26). Clinical examination on admission revealed dehydration , Kussmaul dyspnea , aceto- nemic breath (4 cases), hemodynamic disorders (7 cases) and disturbed consciousness . Mean blood glucose was 25. 2±10 mmol/l, with glycosuria and acetonuria averaging 3 crosses each. Mean pH and bicarbonate values were 7. 17±0. 14 and 8. 6±0. 2 mmol/l respectively. Mean corrected natraemia was 134. 5 mmol/l and mean corrected kalaemia was 3. 1 mmol/l. ACD was classified as moderate in 17cases (38%). Severe forms were more frequent in patients over 4 years of age. Patients were managed according to the ISPAD protocol. the average duration of the protocol was 24 h, with good clinical and biological evolution.