Four-Dimensional Computational Ultrasound Imaging of Brain Haemodynamics

2023/10/13 by Michael Brown, Brown, Michael D., Bastian S. Generowicz +19 · 2 citations
Engineering · Medicine · #Advanced MRI Techniques and Applications #FOS: Physical sciences #Medical Physics (physics.med-ph) #Ultrasound Imaging and Elastography #Ultrasound and Hyperthermia Applications

paper · pdf · doi:10.48550/arxiv.2310.09207

openalex publication_date 2023/10/13 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Four-dimensional ultrasound imaging of complex biological systems such as the brain is technically challenging because of the spatiotemporal sampling requirements. We present computational ultrasound imaging (cUSi), a new imaging method that uses complex ultrasound fields that can be generated with simple hardware and a physical wave prediction model to alleviate the sampling constraints. cUSi allows for high-resolution four-dimensional imaging of brain haemodynamics in awake and anesthetized mice.

Cited by

• 4D Computational Ultrasound Imaging of Carotid Artery Flow
• A 240 Elements Matrix Probe with Aberration Mask for 4D Carotid Artery Computational Ultrasound Imaging

Related

• Non-invasive Deep-Brain Imaging with 3D Integrated Photoacoustic Tomography and Ultrasound Localization Microscopy (3D-PAULM)
• 3D transcranial Dynamic Ultrasound Localization Microscopy in the mouse brain using a Row-Column Array
• 4D Computational Ultrasound Imaging of Carotid Artery Flow
• Deep-Learning Based Super-Resolution Functional Ultrasound Imaging of Transient Brain-Wide Neurovascular Activity on a Microscopic Scale
• Ultrasound-aided Multi-parametric Photoacoustic Microscopy of the Mouse Brain