Detecting the homology of DNA-sequences based on the variety of optimal alignments: a case study

2012/10/14 by Hirmo, Erik, Lember, Jüri, Matzinger, Heinrich
#Applications (stat.AP) #FOS: Biological sciences #FOS: Computer and information sciences #Quantitative Methods (q-bio.QM)

paper · doi:10.48550/arxiv.1210.3771

Abstract

We consider a novel approach of measuring the homology of DNA sequences based of the variety of optimal alignments in the longest common subsequence sense. The proposed approach is compared with BLAST in measuring the homology of four genes.

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