Toward the Establishment of a Harmonized Physicochemical Profiling Platform for Therapeutic Oligonucleotides: A Case Study for Aptamers Where the Higher-Order Structure Influences Physical Properties

2025/06/14 by Shoko Takeuchi, Tomohiko Yamazaki, Katsutoshi Yamaguchi +8
#G-quadruplex #higher-order structure #oligonucleotide #physicochemical profiling #thrombin aptamer

paper · doi:10.48505/nims.4821

Abstract

Molecular Pharmaceutics. 21 [7] (2024)3471-3484

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