FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders

2015/07/01 by Jessica Mariani, Gianfilippo Coppola, Ping Zhang +13 · 1,219 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · Psychology · #Autism #Autism Spectrum Disorder Research #Autism spectrum disorder #Biology #Embryonic stem cell #GABAergic #Gene #Gene expression #Genetics #Genetics and Neurodevelopmental Disorders #Glutamate receptor #Induced pluripotent stem cell #Inhibitory postsynaptic potential #Neuron #Neuroscience #Neuroscience and Neural Engineering #Psychiatry #Psychology #Transcriptome

paper · open access · doi:10.1016/j.cell.2015.06.034

published in Cell 162(2), 375-390 (Cell Press)

openalex publication_date 2015/07/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Citations

• Coexpression Networks Implicate Human Midfetal Deep Cortical Projection Neurons in the Pathogenesis of Autism
• Integrative Functional Genomic Analyses Implicate Specific Molecular Pathways and Circuits in Autism
• The core FOXG1 syndrome phenotype consists of postnatal microcephaly, severe mental retardation, absent language, dyskinesia, and corpus callosum hypogenesis
• International Union of Pharmacology. XLVII. Nomenclature and Structure-Function Relationships of Voltage-Gated Sodium Channels

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