GEFs and GAPs: Critical Elements in the Control of Small G Proteins

2007/06/01 by Johannes L. Bos, Holger Rehmann, Alfred Wittinghofer · 10 citations
Biochemistry, Genetics and Molecular Biology · #Glycosylation and Glycoproteins Research #Ubiquitin and proteasome pathways #Protein Kinase Regulation and GTPase Signaling

paper · pdf · doi:10.1016/j.cell.2007.05.018

Cited by

• Systematic Evaluation of GAPs and GEFs Identifies a Targetable Dependency for Hematopoietic Malignancies
• Direct Inhibition of RAS Reveals the Features of Oncogenic Signaling Driven by RAS G12 and Q61 Mutations
• PCNA is a Nucleotide Exchange Factor for the Clamp Loader ATPase Complex
• Orchestration of cell surface proteins by Rab11
• MicroRNA regulation of K-Ras in pancreatic cancer and opportunities for therapeutic intervention
• Emerging role of small GTPases and their interactome in plants to combat abiotic and biotic stress
• Identification of target genes downstream of semaphorin6A/PlexinA2 signaling in zebrafish
• Ubiquitylation-dependent Rap2 activation regulates lamellipodia dynamics during cell migration
• Melanoma: Pathogenesis and Targeted Therapy
• The fungal RABOME: RAB GTPases acting in the endocytic and exocytic pathways of Aspergillus nidulans (with excursions to other filamentous fungi)