Leptin Regulates Bone Formation via the Sympathetic Nervous System

2002/11/01 by Shu Takeda, Florent Elefteriou, Régis Levasseur +9 · 1,744 citations
Medicine · Neuroscience · #Adipokines, Inflammation, and Metabolic Diseases #Adipose Tissue and Metabolism #Biology #Blood pressure #Endocrinology #Hormone #Internal medicine #Leptin #Medicine #Obesity #Ovariectomized rat #Receptor #Regulation of Appetite and Obesity #Sympathetic nervous system

paper · pdf · doi:10.1016/s0092-8674(02)01049-8

published in Cell 111(3), 305-317 (Cell Press)

openalex publication_date 2002/11/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06

Cited by

• Inhibitory effect of NPY on isoprenaline-induced osteoclastogenesis in mouse bone marrow cells
• Peripheral leptin regulates bone formation
• The bone-cerebrovascular axis: effects of bone aging on neurovascular dysfunction and neurodegeneration
• Regulation of tissue regeneration and repair by the peripheral nervous system
• Leptin Receptor Signaling in POMC Neurons Is Required for Normal Body Weight Homeostasis
• Atenolol, alone or in combination with PTH, has a modest effect on bone in female C57BL/6J mice
• Pregnancy and lactation, a challenge for the skeleton
• Control of Bone Remodeling by the Peripheral Sympathetic Nervous System
• Biology Without Walls: The Novel Endocrinology of Bone
• Human brain evolution and the “Neuroevolutionary Time-depth Principle:” Implications for the Reclassification of fear-circuitry-related traits in DSM-V and for studying resilience to warzone-related posttraumatic stress disorder
• Metabolic regulation by protein tyrosine phosphatases
• β-Adrenergic signaling stimulates osteoclastogenesis via reactive oxygen species
• Bone and muscle loss after spinal cord injury: organ interactions
• Orthodontic tooth movement-activated sensory neurons contribute to enhancing osteoclast activity and tooth movement through sympathetic nervous signalling