The DEAD-Box Protein Dhh1p Couples mRNA Decay and Translation by Monitoring Codon Optimality

2016/09/01 by Aditya Radhakrishnan, Ying-Hsin Chen, Sophie Martin +3 · 2 citations
Biochemistry, Genetics and Molecular Biology · #RNA and protein synthesis mechanisms #RNA Research and Splicing #RNA modifications and cancer

paper · pdf · doi:10.1016/j.cell.2016.08.053

Citations

• Widespread Co-translational RNA Decay Reveals Ribosome Dynamics
• A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress
• Codon Optimality Is a Major Determinant of mRNA Stability
• Dom34 Rescues Ribosomes in 3′ Untranslated Regions
• Selection on Codon Bias

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• Essential Logic and Facts Behind the Expansion of the Genetic Code: A Critical Assessment