2005/02/20 by Z. V. Jaliashvili, Z V Jaliashvili, Jaliashvili, Z. V. +12
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #FOS: Physical sciences #Medical Physics (physics.med-ph) #Optical Imaging and Spectroscopy Techniques #Photodynamic Therapy Research Studies #Spectroscopy Techniques in Biomedical and Chemical Research #physics.med-ph
paper · pdf · doi:10.48550/arxiv.physics/0502102
2 figures
arxiv created 2005/02/20 · openalex publication_date 2005/02/20 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Laser illumination of tissue results in a characteristic fluorescence emission spectrum whose features depend on the type of tissue, viz., healthy, adenoma or malignant. Hence measurement of the fluorescence is potentially a rapid and reliable diagnostic method. We have applied the technique to thyroid tissues and found that judicious normalization of the fluorescence spectrum reveals a close correlation between spectral shape and tissue type. Hence the pathological state of the tissue can be unambiguously identified from the laser-induced fluorescence spectrum. The method is rapid and portable and is therefore eminently suitable for use during operations.