A Combined Model for Predicting CYP3A4 Clinical Net Drug-Drug Interaction Based on CYP3A4 Inhibition, Inactivation, and Induction Determined in Vitro

2008/05/20 by Odette A. Fahmi, Tristan S. Maurer, Mary Kish +4
Engineering · Medicine · Pharmacology, Toxicology and Pharmaceutics · #Drug Transport and Resistance Mechanisms #Innovative Microfluidic and Catalytic Techniques Innovation #Pharmacogenetics and Drug Metabolism

paper · doi:10.1124/dmd.107.018663

openalex publication_date 2008/05/20 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27

Citations

• The Utility of in Vitro Cytochrome P450 Inhibition Data in the Prediction of Drug-Drug Interactions
• Mechanism-Based Inactivation of Human Cytochrome P450 Enzymes and the Prediction of Drug-Drug Interactions