A review of physiologically based pharmacokinetic modeling of renal drug disposition

2025/01/21 by Weize Huang, Christine M. Bowman, Christine Bowman +6
Medicine · Pharmacology, Toxicology and Pharmaceutics · #Drug Transport and Resistance Mechanisms #Pharmacogenetics and Drug Metabolism #Pharmacological Effects and Toxicity Studies

paper · doi:10.1016/j.dmd.2025.100042

openalex publication_date 2025/01/21 · openalex created_date 2025/01/22 · openalex updated_date 2026/08/04

Citations

• Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug–Drug and Drug–Disease Interactions
• Physiologically Based Pharmacokinetic Models of Probenecid and Furosemide to Predict Transporter Mediated Drug-Drug Interactions
• Physiologically based pharmacokinetic (PBPK) modelling of oral drug absorption in older adults – an AGePOP review