1982/05/01 by Amiya K. Hajra, James E. Bishop · 1 citation
Biochemistry, Genetics and Molecular Biology · #Peroxisome Proliferator-Activated Receptors #Biochemical and Molecular Research #Sphingolipid Metabolism and Signaling
paper · doi:10.1111/j.1749-6632.1982.tb21415.x
In recent years, acyl dihydroxyacetone phosphate [acyl-DHAPt) has been shown to be a precursor of glycerolipids and glycerol-ether lipids.'. ' Acyl-DHAP was discovered as a rapidly labeled lipid that was formed in crude mitochondrial fraction from 3'Pi or y-32P[ATP].3 This rapid labeling was due to the enzymatic dephosphorylation and rephosphorylation of endogenous acyl-DHAP present in the crude mitochondrial fraction (equation 1): Acyl-DHAP 2-/- Acyl-DHA (1) ADP ATP Acyl-DHAP was later shown to be biosynthesized by a direct acylation of DHAP with acyl-CoA. catalyzed by DHAP acyltransferase (EC 2.3.1.42) (equation