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Error reduction in biosensors using secondary labeling

2019/07/10 by Chakrabortty, Tuhin, Varma, Manoj M
#Biological Physics (physics.bio-ph) #FOS: Physical sciences #Medical Physics (physics.med-ph)

paper · doi:10.48550/arxiv.1907.04516

Abstract

In this article, we derive the limit of detection for a two-step molecular recognition process and show that in-spite of all the recognition reactions being in equilibrium the overall error rates can be reduced exactly as much as possible in non-equilibrium methods such as kinetic proofreading.

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