2015/07/16 by Chang Hyeuk Kim, Kim, Chang Hyeuk, Hwa-Ryun Lee +13
Agricultural and Biological Sciences · Medicine · Physics and Astronomy · #Advanced Radiotherapy Techniques #FOS: Physical sciences #Medical Physics (physics.med-ph) #Radiation Effects and Dosimetry #Radiation Therapy and Dosimetry
paper · pdf · doi:10.48550/arxiv.1507.04453
openalex publication_date 2015/07/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
The carbon beams show more advantages on the biological properties compared with proton beams in radiation therapy. The carbon beam shows high linear energy transfer (LET) to medium and it increases the relative biological effectiveness (RBE). To design spread-out Bragg peak (SOBP) of biological dose using carbon beam, a practical method was purposed by using the linear-quadratic (LQ) model and Geant4 based Monte Carlo simulation code. The various Bragg peak profiles and LET was calculated for each slice at the target region. To generate appropriate biological SOBP, a set of weighting factor, which is a power function in terms of energy step, was applied to the obtained each physical dose. The designed biological SOBP showed 1.34 % of uniformity.