Evaluation of the Bactericidal Activity of Fosfomycin in Combination with Selected Antimicrobial Comparison Agents Tested against Gram-Negative Bacterial Strains by Using Time-Kill Curves

2019/03/12 by Robert K. Flamm, Paul R. Rhomberg, Jill M. Lindley +5 · 1 citation
Biochemistry, Genetics and Molecular Biology · Medicine · #Antibiotic Resistance in Bacteria #Bacterial Identification and Susceptibility Testing #Urinary Tract Infections Management

paper · pdf · doi:10.1128/aac.02549-18

Abstract

The effects of combining fosfomycin with various antimicrobial agents were evaluated in vitro by broth microdilution checkerboard and time-kill kinetic studies. Checkerboard analyses were used to evaluate the following 30 Gram-negative isolates: 5 Pseudomonas aeruginosa , 5 Acinetobacter baumannii - Acinetobacter calcoaceticus species complex, and 20 Enterobacteriaceae isolates.

Citations

• Preliminary Study of Colistin versus Colistin plus Fosfomycin for Treatment of Carbapenem-Resistant Acinetobacter baumannii Infections

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• Fosfomycin as an adjunctive agent against carbapenem-resistant Acinetobacter baumannii: an updated narrative review

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