Salicylic Acid, a Multifaceted Hormone to Combat Disease
2009/08/03 by A. Corina Vlot, D'Maris Amick Dempsey, D’Maris Amick Dempsey +1 · 2,601 citations
Agricultural and Biological Sciences · #Arabidopsis #Biochemistry #Biology #Cell biology #Computational biology #Defence mechanisms #Disease #Ecology #Gene #Genetics #Hormone #Internal medicine #Plant Parasitism and Resistance #Plant Stress Responses and Tolerance #Plant defense against herbivory #Plant disease resistance #Plant hormone #Plant-Microbe Interactions and Immunity #Programmed cell death #Resistance (ecology) #Salicylic acid #Signal transduction #Systemic acquired resistance
paper · doi:10.1146/annurev.phyto.050908.135202
published in Annual Review of Phytopathology 47(1), 177-206 (Annual Reviews)
openalex publication_date 2009/08/03 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
Abstract
For more than 200 years, the plant hormone salicylic acid (SA) has been studied for its medicinal use in humans. However, its extensive signaling role in plants, particularly in defense against pathogens, has only become evident during the past 20 years. This review surveys how SA in plants regulates both local disease resistance mechanisms, including host cell death and defense gene expression, and systemic acquired resistance (SAR). Genetic studies reveal an increasingly complex network of proteins required for SA-mediated defense signaling, and this process is amplified by several regulatory feedback loops. The interaction between the SA signaling pathway and those regulated by other plant hormones and/or defense signals is also discussed.
Citations
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