PATHOGEN POPULATION GENETICS, EVOLUTIONARY POTENTIAL, AND DURABLE RESISTANCE
2002/09/01 by Bruce A. McDonald, Celeste C. Linde, Celeste Linde · 2,134 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · #Biology #Evolution and Genetic Dynamics #Gene #Genetics #Genotype #Mutation #Pathogen #Plant Virus Research Studies #Population #Wheat and Barley Genetics and Pathology
paper · doi:10.1146/annurev.phyto.40.120501.101443
published in Annual Review of Phytopathology 40(1), 349-379 (Annual Reviews)
openalex publication_date 2002/09/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/08/06
Abstract
We hypothesize that the evolutionary potential of a pathogen population is reflected in its population genetic structure. Pathogen populations with a high evolutionary potential are more likely to overcome genetic resistance than pathogen populations with a low evolutionary potential. We propose a flexible framework to predict the evolutionary potential of pathogen populations based on analysis of their genetic structure. According to this framework, pathogens that pose the greatest risk of breaking down resistance genes have a mixed reproduction system, a high potential for genotype flow, large effective population sizes, and high mutation rates. The lowest risk pathogens are those with strict asexual reproduction, low potential for gene flow, small effective population sizes, and low mutation rates. We present examples of high-risk and low-risk pathogens. We propose general guidelines for a rational approach to breed durable resistance according to the evolutionary potential of the pathogen.
Cited by
- Susceptibility Genes 101: How to Be a Good Host
- Quantitative Disease Resistance and Quantitative Resistance Loci in Breeding
- Climate Change Effects on Plant Disease: Genomes to Ecosystems
- The Origins of Plant Pathogens in Agro-Ecosystems
- Modeling the Impact of Crop Diseases on Global Food Security
- Population genomics and molecular epidemiology of wheat powdery mildew in Europe
- Local adaptation of both plant and pathogen: an arms‐race compromise in switchgrass rust
- Genomic Surveillance and Molecular Evolution of Fungicide Resistance in European Populations of Wheat Powdery Mildew
- Disease development and genotypic diversity of Puccinia graminis f. sp. avenae in Swedish oat fields
- Global food and fibre security threatened by current inefficiencies in fungal identification
- Sex or no sex: Evolutionary adaptation occurs regardless
- Dynamic Gene-for-Gene Interactions Undermine Durable Resistance
- Behind the shadow play: Shedding light on the population genetics of partially clonal organisms through clone age distributions
- Long-distance gene flow and recombination shape the evolutionary history of a maize pathogen
- Genomic profiles of Pyricularia oryzae in Sub-Saharan Africa: exploring population differences and their evolutionary implications in the region
- Colonization of Barley by the Broad-Host Hemibiotrophic Pathogen Phytophthora palmivora Uncovers a Leaf Development–Dependent Involvement of Mlo
- Unraveling the Fusarium oxysporum f. sp. fragariae –Strawberry Interaction: Evolution, Infection, and Genetic Resistance
- Plasticity in initial infection traits in response to high temperature for worldwide representative Puccinia striiformis isolates
- Genetic structure and phylogeny of Italian and Czech populations of the cucurbit powdery mildew fungus Golovinomyces orontii inferred by multilocus sequence typing
- The effect of spatial scales on the reproductive fitness of plant pathogens
- Interaction between climatic variation and pathogen diversity shape endemic disease dynamics in the agricultural settings
- Expansive Phenotypic Landscape of Botrytis cinerea Shows Differential Contribution of Genetic Diversity and Plasticity
- Recombination Events Generating a Novel Rp1 Race Specificity
- Interaction Between Climatic Variation and Pathogen Diversity Shape Endemic Disease Dynamics in the Agricultural Settings
- Cryptic host-associated differentiation and diversity: unravelling the evolutionary dynamics of the plant pathogen Lasiodiplodia
- A Population Genomics Approach to Understand the Diversity, Migration, and Reproduction of the Rice Pathogen Cercospora janseana
- Effects of Pathogen Load and Host Genetic Background on Tandem Kinase-Mediated Resistance in Wheat
- Population Genomics of Macrophomina spp. Reveals Cryptic Host Specialization and Evidence for Meiotic Recombination
- Turnip Yellows Virus Resistances Differ in Effectiveness Against Three Diverse Isolates
- Closing the Information Gap Between the Field and Scientific Literature for Improved Disease Management, with a Focus on Rice and Bacterial Blight
- Phylogenomics and adaptive evolution of the Colletotrichum gloeosporioides species complex
- Regional Population Genetics Structured by Mating Type in Alternaria brassicicola in Cole Crops ( Brassica spp.) in the Northeastern, Midwestern, and Southeastern United States
- Virulence spectrum of Moroccan Zymoseptoria tritici isolates and efficacy of Septoria tritici blotch resistance genes
- How to develop smarter host mixtures to control plant disease?
- Virulence gains in the Puccinia striiformis f. sp. tritici PstS10 lineage correlate with expression polymorphism in a candidate Avr effector
- Virulence phenotypes in powdery mildew (Blumeria graminis) populations and resistance genes in triticale (x Triticosecale)
- The challenges of maintaining wheat productivity: pests, diseases, and potential epidemics
- High genetic variability of Puccinia triticina at a specific location in Slovakia: a case study
- Testing Differences Between Pathogen Compositions with Small Samples and Sparse Data
- Ranking Quantitative Resistance to Septoria tritici Blotch in Elite Wheat Cultivars Using Automated Image Analysis
- DMI fungicide resistance in Zymoseptoria tritici is unlinked to geographical origin and genetic background: a case study in Europe
- Neutral genetic structuring of pathogen populations during rapid adaptation
- Introgression of bacterial blight resistance genes Xa7, Xa21, Xa22 and Xa23 into hybrid rice restorer lines by molecular marker-assisted selection
- Comparative biology of different plant pathogens to estimate effects of climate change on crop diseases in Europe
- Mycosphaerella graminicola: from genomics to disease control
- Analysis of genetic and virulence variability of Stemphylium lycopersici associated with leaf spot of vegetable crops
- The rate at which asexual populations cross fitness valleys
- Genome-Wide Association Mapping Uncovers Fw1, a Dominant Gene Conferring Resistance to Fusarium Wilt in Strawberry
- The evolutionary origins of pesticide resistance
- Ecology and Epidemiology of Diseases of Nut Crops and Olives Caused by Botryosphaeriaceae Fungi in California and Spain
- Genetic Structure of Botrytis cinerea Populations from Different Host Plants in California
- The Coevolution of Plants and Viruses
- The global burden of pathogens and pests on major food crops
- Fungal and Oomycete Diseases of Tropical Tree Fruit Crops
Related