From Chaos to Harmony: Responses and Signaling upon Microbial Pattern Recognition

2017/05/19 by Xiao Yu, Baomin Feng, Ping He +1 · 628 citations
Agricultural and Biological Sciences · #Biology #Cell biology #Genetics #Immune system #Immunity #Innate immune system #Legume Nitrogen Fixing Symbiosis #Pathogen #Pathogen-associated molecular pattern #Pattern recognition receptor #Plant Pathogenic Bacteria Studies #Plant-Microbe Interactions and Immunity #Signal transduction

paper · doi:10.1146/annurev-phyto-080516-035649

published in Annual Review of Phytopathology 55(1), 109-137 (Annual Reviews)

openalex publication_date 2017/05/19 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/06

Abstract

Pathogen- or microbe-associated molecular patterns (PAMPs/MAMPs) are detected as nonself by host pattern recognition receptors (PRRs) and activate pattern-triggered immunity (PTI). Microbial invasions often trigger the production of host-derived endogenous signals referred to as danger- or damage-associated molecular patterns (DAMPs), which are also perceived by PRRs to modulate PTI responses. Collectively, PTI contributes to host defense against infections by a broad range of pathogens. Remarkable progress has been made toward demonstrating the cellular and physiological responses upon pattern recognition, elucidating the molecular, biochemical, and genetic mechanisms of PRR activation, and dissecting the complex signaling networks that orchestrate PTI responses. In this review, we present an update on the current understanding of how plants recognize and respond to nonself patterns, a process from which the seemingly chaotic responses form into a harmonic defense.

Citations

• MAPK Cascades in Plant Disease Resistance Signaling
• Contrasting Mechanisms of Defense Against Biotrophic and Necrotrophic Pathogens
• The plant immune system

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