Functional Regulators of Bacterial Flagella

2019/05/28 by Sundharraman Subramanian, Daniel B. Kearns · 1 citation
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Bacterial Genetics and Biotechnology #Micro and Nano Robotics #Lipid Membrane Structure and Behavior

paper · doi:10.1146/annurev-micro-020518-115725

Abstract

Bacteria move by a variety of mechanisms, but the best understood types of motility are powered by flagella (72). Flagella are complex machines embedded in the cell envelope that rotate a long extracellular helical filament like a propeller to push cells through the environment. The flagellum is one of relatively few biological machines that experience continuous 360° rotation, and it is driven by one of the most powerful motors, relative to its size, on earth. The rotational force (torque) generated at the base of the flagellum is essential for motility, niche colonization, and pathogenesis. This review describes regulatory proteins that control motility at the level of torque generation.

Citations

• Caulobacter Flagellar Function, but not Assembly, Requires FliL, a Non-polarly Localized Membrane Protein Present in all Cell Types

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• Nascent flagellar basal bodies are immobilized by rod assembly in Bacillus subtilis

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