Dietary fructose enhances tumour growth indirectly via interorgan lipid transfer

2024/12/04 by Ronald Fowle-Grider, Joe L. Rowles, Isabel Shen +22 · 2 voices
Medicine · Biochemistry, Genetics and Molecular Biology · #Diet, Metabolism, and Disease #Liver Disease Diagnosis and Treatment #Lipid metabolism and biosynthesis

paper · doi:10.1038/s41586-024-08258-3

Discussions

• The liver converts fructose into lipids to fuel tumours. #Nature "Fructose supplementation increases circulating nutrients such as LPCs, which can enhance tumour growth through a cell non-autonomous [bsky, 22 points, 0 comments]
• #TooSweet! @gjpattij.bsky.social @nightscientist.bsky.social &co show @ Nature that the dietary sweetener fructose is metabolized in the liver to produce membrane building block lipids that are utiliz [bsky, 16 points, 1 comments]