Polina Prokofeva
- Target deconvolution of HDAC pharmacopoeia reveals MBLAC2 as common off-target
2022/04/28 by Severin Lechner, Martin Ian P. Malgapo, Christian Grätz +24 · 1 voice · 6 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Epigenetics and DNA Methylation #Histone Deacetylase Inhibitors Research #Peptidase Inhibition and Analysis
- Inhibitors supercharge kinase turnover through native proteolytic circuits
2025/11/26 by Natalie S. Scholes, Martino Bertoni, Arnau Comajuncosa-Creus +27 · 1 voice · 7 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Protein Degradation and Inhibitors #Ubiquitin and proteasome pathways #Click Chemistry and Applications
- Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits
2024/07/10 by Natalie S. Scholes, Martino Bertoni, Arnau Comajuncosa-Creus +18 · 1 voice · 1 citation
Biochemistry, Genetics and Molecular Biology · #Protein Degradation and Inhibitors #Ubiquitin and proteasome pathways #Protein Kinase Regulation and GTPase Signaling